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5-Amino-1MQ possesses a well-characterized pharmacological profile and high selectivity for NNMT, making it a valuable reference compound for studies involving NNMT enzyme biology, methyltransferase pathway regulation, structure-activity relationships, and inhibitor-target interactions

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AOD-9604's entire human trial program involved 893 participants across six studies, with the largest being the 536-subject Phase 2b trial that failed to meet its endpoint